Linked Life Data

3355612

Source:http://linkedlifedata.com/resource/pubmed/id/3355612

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1988-5-2
pubmed:abstractText
The distribution of plasma high density lipoprotein (HDL) subfractions was determined in 2 groups of healthy male subjects with different coronary risk indices (CI) as assessed by the ratio of total plasma cholesterol/HDL-cholesterol. The subjects in the 2 groups were of similar age and fitness (as assessed by VO2max). The higher risk group (CI greater than 4.0) contained a lower relative concentration of a specific HDL subfraction, HDL2b, separated by gradient gel electrophoresis, and a lower level of an apo E-rich HDL fraction, isolated by affinity chromatography, than the lower risk group (CI less than 4.0). The concentration of total HDL-cholesterol was higher in the lower risk group due to a difference in HDL2-cholesterol when separation was achieved by polyanion precipitation, but not when separation was made by ultracentrifugation. These observations suggest that the level of these specific HDL subfractions might, when taken in conjunction with plasma cholesterol concentration, provide a better index of coronary risk than that of total HDL as conventionally employed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0021-9150
pubmed:author
pubmed:issnType
Print
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
165-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Plasma high density lipoprotein subfractions in subjects with different coronary risk indices as assessed by plasma lipoprotein concentrations.
pubmed:affiliation
Department of Biochemistry, University of Aberdeen, U.K.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't