Linked Life Data

3354005

Source:http://linkedlifedata.com/resource/pubmed/id/3354005

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-4-25
pubmed:abstractText
Administration of 2000 mg/kg of di(2-ethylhexyl)phthalate (DEHP) for a period of 7 or 15 days in rats, mice, guinea pigs and rabbits produced a differential effect as judged by alterations in body weight gain, liver weight and activities of mixed function oxidases. DEHP exposure for 7 days caused an increase in the activity of aniline hydroxylase, arylhydrocarbon hydroxylase and ethylmorphine N-demethylase in rats, mice and guinea pigs, but a decrease in that of rabbits. However, exposure for 15 days produced a smaller degree of increase in the activity of these enzymes in rats and mice and even produced a decrease in the activity of these enzymes in guinea pigs. This differential response of DEHP in various animal species suggests a species difference in the toxicity of the plasticizer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0378-4274
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
209-17
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Effect of di(2-ethylhexyl)phthalate (DEHP) on hepatic mixed function oxidases in different animal species.
pubmed:affiliation
Industrial Toxicology Research Centre, Mahatma Gandhi Marg, Lucknow, India.
pubmed:publicationType
Journal Article