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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1988-5-3
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pubmed:abstractText |
Lipid bodies are non-membrane bound intracellular organelles, which have been recognized morphologically in a diversity of mammalian and nonmammalian cells, but are of uncertain function. In mammalian cells, in addition to serving as a storage site of cholesterol and triglyceride, lipid bodies can be a repository of esterified arachidonic acid. Adult worms of the human filarial parasite Brugia malayi have been found to esterify exogenous [3H]arachidonic acid into parasite phospholipids and neutral lipids. Electron microscopic autoradiography demonstrated that [3H]arachidonate was preferentially incorporated into filarial lipid bodies. The dominant incorporation of arachidonate into lipid bodies of a nematode establishes that lipid bodies are a site of arachidonic acid accumulation in nonmammalian, as well as mammalian, cells.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0014-4894
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
251-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3350105-Animals,
pubmed-meshheading:3350105-Arachidonic Acids,
pubmed-meshheading:3350105-Autoradiography,
pubmed-meshheading:3350105-Brugia,
pubmed-meshheading:3350105-Esters,
pubmed-meshheading:3350105-Female,
pubmed-meshheading:3350105-Lipid Metabolism,
pubmed-meshheading:3350105-Male,
pubmed-meshheading:3350105-Microscopy, Electron,
pubmed-meshheading:3350105-Organoids,
pubmed-meshheading:3350105-Phospholipids
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pubmed:year |
1988
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pubmed:articleTitle |
Brugia malayi: arachidonic acid uptake into lipid bodies of adult parasites.
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pubmed:affiliation |
Department of Medicine, Beth Israel Hospital, Boston, Massachusetts.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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