rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
1988-3-28
|
pubmed:abstractText |
The clinical and biochemical effects of adjuvant reserpine treatment were investigated in 12 chronic schizophrenic patients on long-term neuroleptic medication. The global severity of the symptoms using the Brief Psychiatric Rating Scale did not change significantly in the whole group, however, a moderate decrease in positive symptoms (factors though disturbance, activation and hostile-suspiciousness) was observed for 5 patients. Cerebrospinal fluid (CSF) noradrenaline levels showed a consistent decrease, but other biochemical parameters (CSF dopamine metabolites, platelet MAO and serum dopamine-beta-hydroxylase activities) did not change significantly. The changes of clinical symptoms and biochemical parameters did not show any correlation.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0300-9564
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
71
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
73-8
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3343596-Adjuvants, Pharmaceutic,
pubmed-meshheading:3343596-Adult,
pubmed-meshheading:3343596-Catecholamines,
pubmed-meshheading:3343596-Dopamine beta-Hydroxylase,
pubmed-meshheading:3343596-Humans,
pubmed-meshheading:3343596-Male,
pubmed-meshheading:3343596-Middle Aged,
pubmed-meshheading:3343596-Monoamine Oxidase,
pubmed-meshheading:3343596-Prolactin,
pubmed-meshheading:3343596-Reserpine,
pubmed-meshheading:3343596-Schizophrenia,
pubmed-meshheading:3343596-Time Factors
|
pubmed:year |
1988
|
pubmed:articleTitle |
Effect of adjuvant reserpine treatment on catecholamine metabolism in schizophrenic patients under long-term neuroleptic treatment.
|
pubmed:affiliation |
National Institute for Nervous and Mental Diseases, Budapest, Hungary.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|