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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1988-3-8
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pubmed:abstractText |
The pathophysiology of idiopathic spasmodic torticollis is uncertain. Cerebral, basal ganglia, brain-stem, and cervicomedullary lesions have been implicated. Some investigators have found evoked-potential abnormalities, while others have not. We recorded brain-stem auditory-evoked potentials in six patients with otherwise normal result of examinations and laboratory studies. Brain-stem auditory-evoked potentials were recorded from Cz-A1 and Cz-A2 with rarefaction clicks delivered at 11.1/s and 70 dB above sensory threshold with 40-dB contralateral masking. Analysis time was 10 ms, filter bandpass was 150 to 3000 Hz, and 4000 averages were replicated. Patients and age-matched controls were compared by Student's t test. One patient had I-III and I-V interpeak latencies (IPLs) beyond clinical norms (99% tolerance limit). Mean IPLs ipsilateral to torticollis were 2.32 +/- 0.2 (I-III), 1.96 +/- 0.4 (III-V), and 4.16 +/- 0.3 (I-V). Contralateral IPLs were 2.0 +/- 0.2 (I-III), 2.0 +/- 0.2 (III-V), and 3.9 +/- 0.5 (I-V). Control values were 2.04 +/- 0.2 (I-III), 1.86 +/- 0.2 (III-V), and 3.86 +/- 0.4 (I-V). Absolute latencies, V/I amplitude ratios, and III-V IPLs did not differ significantly between patients and controls, nor did IPLs contralateral to torticollis. Ipsilateral I-III and I-V IPLs were greater in patients than in controls. These findings are consistent with those of some clinical reports and with experimental evidence that brain-stem lesions produce torticollis. They imply brain-stem dysfunction ipsilateral to head deviation in at least some patients with torticollis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0003-9942
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
174-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3341931-Brain Stem,
pubmed-meshheading:3341931-Evoked Potentials, Auditory,
pubmed-meshheading:3341931-Female,
pubmed-meshheading:3341931-Humans,
pubmed-meshheading:3341931-Male,
pubmed-meshheading:3341931-Neck Muscles,
pubmed-meshheading:3341931-Spasm,
pubmed-meshheading:3341931-Torticollis
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pubmed:year |
1988
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pubmed:articleTitle |
Brain-stem auditory-evoked potentials in spasmodic torticollis.
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pubmed:affiliation |
Department of Neurology, Ohio State University College of Medicine, Columbus 43210.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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