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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1988-3-9
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pubmed:abstractText |
It has previously been shown that the L1 family in the mouse (L1Md) contains two alternative 5' ends called the A- and F-type sequences (1,2). We show here that the F-type element is a major class of murine L1 elements and report on the details of organization of the 5' motif of these F-type elements. Although the A- and F-type 5' sequences share no detectable sequence homology the organization of an F-type 5' end is strikingly similar to that of an A-type. That is, the F-type 5' sequences consist of a tandem array of a small number of 206 bp monomers while the A-type 5' motif consists of a tandem array of 208 bp monomers. All of the A-type elements characterized to date have a truncated monomer at the 5' end of the array. Many of the F-type elements are also terminated at the 5' end by a truncated copy but unlike the A-type elements some F-type elements terminate with a monomer which is within a few nucleotides of being complete. In addition the F-type consensus sequence, in contrast to the A-type sequence, shows homology (70%) to the body of the L1Md starting at the position where the monomer joins the rest of the L1 element.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-3023821,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-3100811,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-3754048,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-3839456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6088070,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6090124,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6188844,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6208477,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6235374,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6248428,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6250710,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6266279,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6290999,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6305233,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6306481,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6306655,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6308571,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-631324,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6320108,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6322182,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6324106,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6326107,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6326120,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6345791,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6492166,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6546796,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-6575390,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-719759,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3340553-987581
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0305-1048
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
25
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
739-49
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1988
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pubmed:articleTitle |
The F-type 5' motif of mouse L1 elements: a major class of L1 termini similar to the A-type in organization but unrelated in sequence.
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pubmed:affiliation |
Department of Microbiology and Immunology, University of North Carolina, Chapel Hill 27514.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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