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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1988-3-11
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pubmed:abstractText |
Treatment, by local depot methylprednisolone injection, of severe anal pain in Crohn's disease not associated with overt sepsis is reported. It has given dramatic relief in 5 patients, but has not been successful in 2 patients where anal disease was in continuity with severe rectal involvement. Treatment has been effective for greater than 1 yr, and no complication of the technique has been found on regular follow-up. When compared with previous attempts at treatment, the beneficial results attained with methylprednisolone injection suggest that the effect is more than a placebo response. Careful patient selection to exclude overt sepsis or severe rectal disease is recommended before proceeding to steroid injection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0016-5085
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
709-11
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3338639-Adult,
pubmed-meshheading:3338639-Aged,
pubmed-meshheading:3338639-Anti-Inflammatory Agents,
pubmed-meshheading:3338639-Anus Diseases,
pubmed-meshheading:3338639-Crohn Disease,
pubmed-meshheading:3338639-Female,
pubmed-meshheading:3338639-Humans,
pubmed-meshheading:3338639-Male,
pubmed-meshheading:3338639-Methylprednisolone,
pubmed-meshheading:3338639-Middle Aged,
pubmed-meshheading:3338639-Pain
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pubmed:year |
1988
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pubmed:articleTitle |
Local depot methylprednisolone injection for painful anal Crohn's disease.
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pubmed:affiliation |
University Department of Surgery, University of Wales College of Medicine, Heath Park, Cardiff, United Kingdom.
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pubmed:publicationType |
Journal Article
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