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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1988-3-15
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pubmed:abstractText |
We have examined the effect on iron stores of blood transfusions given to premature neonates during hospitalization in the neonatal intensive care unit as reflected by serum ferritin levels measured for 6 months after discharge. Premature infants who were transfused with more than 100 ml packed cells (group D; n = 11) had higher ferritin levels for a longer period than premature infants who were transfused with smaller volumes (group c; n = 9) or premature and mature infants who were not transfused at all (group B; n = 24 and group A; n = 21, respectively). At 4-5 months the serum ferritin levels in group D (489.8 +/- 132.1 micrograms/L; mean +/- SEM) were significantly higher (P less than 0.001) than those of the other groups. The level of group A term infants (77.5 +/- 12.5 micrograms/L) was higher than those of group B premature infants who did not receive a blood transfusion (33.0 +/- 7.1 micrograms/L) or group C who received less than 100 ml (36.5 +/- 8.8 micrograms/L packed red blood cells. However, these differences were not statistically significant. Our data demonstrate that very-low-birthweight infants who receive a large volume of packed cells during hospitalization may accumulate iron stores sufficient for red cell production during the first 6 months of life. Administration of large amounts of supplemental iron, in such cases, may be curtailed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0735-1631
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
40-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3337757-Anemia, Hypochromic,
pubmed-meshheading:3337757-Blood Transfusion,
pubmed-meshheading:3337757-Ferritins,
pubmed-meshheading:3337757-Follow-Up Studies,
pubmed-meshheading:3337757-Humans,
pubmed-meshheading:3337757-Infant,
pubmed-meshheading:3337757-Infant, Low Birth Weight,
pubmed-meshheading:3337757-Infant, Newborn,
pubmed-meshheading:3337757-Infant, Premature,
pubmed-meshheading:3337757-Infant Food
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pubmed:year |
1988
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pubmed:articleTitle |
Serum ferritin levels in preterm infants after multiple blood transfusions.
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pubmed:affiliation |
Department of Pediatrics, Hebrew University Hadassah Medical Centers, Mount Scopus, Jerusalem, Israel.
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pubmed:publicationType |
Journal Article,
Comparative Study
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