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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1988-2-16
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pubmed:abstractText |
We studied forty-four patients with myasthenia gravis (MG) and their families. Thirty percent of patients had a confirmed family history of autoimmune disease; in one case this was MG. In all the families with autoimmune disease, the affected relatives were related to the patients through the maternal line. HLA-B8 and DR3 were increased in patients due to the high incidence of these antigens in female, nonthymoma patients with onset before 40 years. HLA-B5 was increased in patients with older onset. The haplotype A1-B8-DR3 was not found to be increased given the presence of B8 or DR3.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0028-3878
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
38-42
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3336461-Adolescent,
pubmed-meshheading:3336461-Adult,
pubmed-meshheading:3336461-Aged,
pubmed-meshheading:3336461-Autoimmune Diseases,
pubmed-meshheading:3336461-Child,
pubmed-meshheading:3336461-Female,
pubmed-meshheading:3336461-HLA Antigens,
pubmed-meshheading:3336461-Humans,
pubmed-meshheading:3336461-Male,
pubmed-meshheading:3336461-Middle Aged,
pubmed-meshheading:3336461-Myasthenia Gravis,
pubmed-meshheading:3336461-Pedigree,
pubmed-meshheading:3336461-Thymus Gland
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pubmed:year |
1988
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pubmed:articleTitle |
Genetic factors in myasthenia gravis: a family study.
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pubmed:affiliation |
Department of Medical Genetics, St. Mary's Hospital, Manchester, England.
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pubmed:publicationType |
Journal Article
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