| pubmed-article:3335605 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3335605 | lifeskim:mentions | umls-concept:C0025266 | lld:lifeskim |
| pubmed-article:3335605 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:3335605 | lifeskim:mentions | umls-concept:C0038148 | lld:lifeskim |
| pubmed-article:3335605 | lifeskim:mentions | umls-concept:C0205307 | lld:lifeskim |
| pubmed-article:3335605 | lifeskim:mentions | umls-concept:C0022203 | lld:lifeskim |
| pubmed-article:3335605 | lifeskim:mentions | umls-concept:C0486333 | lld:lifeskim |
| pubmed-article:3335605 | lifeskim:mentions | umls-concept:C0812407 | lld:lifeskim |
| pubmed-article:3335605 | lifeskim:mentions | umls-concept:C1708632 | lld:lifeskim |
| pubmed-article:3335605 | lifeskim:mentions | umls-concept:C1522485 | lld:lifeskim |
| pubmed-article:3335605 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:3335605 | pubmed:dateCreated | 1988-2-2 | lld:pubmed |
| pubmed-article:3335605 | pubmed:abstractText | 3 alpha-Androstanediol glucuronide (Adiol G) is a major metabolite of dihydrotestosterone (DHT). Adiol G actually represents 2 different compounds, since the glucuronide can be conjugated at the 3-carbon position (Adiol 3-G) or at the 17-carbon position (Adiol 17-G). To determine which glucuronide represents the predominant physiological DHT metabolite and which isomer is the major circulating form, we developed a RIA to directly measure Adiol 3-G in serum extracts. In 10 normal men, mean serum Adiol 3-G and total Adiol G levels were 4.44 +/- 0.49 (+/- SE) nmol/L (208 +/- 23 ng/dL) and 27.9 +/- 2.8 nmol/L (1310 +/- 129 ng/dL), respectively (13.9 +/- 3.0% of Adiol G was Adiol 3-G). In 10 normal women sampled during the early follicular phase, mean serum Adiol 3-G and total Adiol G levels were 2.64 +/- 0.64 nmol/L (124 +/- 30 ng/dL) and 14.9 +/- 1.5 nmol/L (697 +/- 69 ng/dL), respectively (17.4 +/- 3.6% of Adiol G was Adiol 3-G). In 4 normal men infused for 8 h with tritiated DHT, 17.4 +/- 3.4% of the resulting tritiated Adiol G was Adiol 3-G. These results indicate that Adiol 17-G is the predominant circulating form of Adiol G in normal men and women and that it is also the major Adiol G isomer derived from DHT. | lld:pubmed |
| pubmed-article:3335605 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3335605 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3335605 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:3335605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3335605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3335605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3335605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3335605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3335605 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3335605 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:3335605 | pubmed:issn | 0021-972X | lld:pubmed |
| pubmed-article:3335605 | pubmed:author | pubmed-author:LoriauxD LDL | lld:pubmed |
| pubmed-article:3335605 | pubmed:author | pubmed-author:ThompsonD LDL | lld:pubmed |
| pubmed-article:3335605 | pubmed:author | pubmed-author:RittmasterR... | lld:pubmed |
| pubmed-article:3335605 | pubmed:author | pubmed-author:ListwakSS | lld:pubmed |
| pubmed-article:3335605 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3335605 | pubmed:volume | 66 | lld:pubmed |
| pubmed-article:3335605 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3335605 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3335605 | pubmed:pagination | 212-6 | lld:pubmed |
| pubmed-article:3335605 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:3335605 | pubmed:meshHeading | pubmed-meshheading:3335605-... | lld:pubmed |
| pubmed-article:3335605 | pubmed:meshHeading | pubmed-meshheading:3335605-... | lld:pubmed |
| pubmed-article:3335605 | pubmed:meshHeading | pubmed-meshheading:3335605-... | lld:pubmed |
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| pubmed-article:3335605 | pubmed:meshHeading | pubmed-meshheading:3335605-... | lld:pubmed |
| pubmed-article:3335605 | pubmed:meshHeading | pubmed-meshheading:3335605-... | lld:pubmed |
| pubmed-article:3335605 | pubmed:meshHeading | pubmed-meshheading:3335605-... | lld:pubmed |
| pubmed-article:3335605 | pubmed:meshHeading | pubmed-meshheading:3335605-... | lld:pubmed |
| pubmed-article:3335605 | pubmed:meshHeading | pubmed-meshheading:3335605-... | lld:pubmed |
| pubmed-article:3335605 | pubmed:meshHeading | pubmed-meshheading:3335605-... | lld:pubmed |
| pubmed-article:3335605 | pubmed:meshHeading | pubmed-meshheading:3335605-... | lld:pubmed |
| pubmed-article:3335605 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3335605 | pubmed:articleTitle | Androstanediol glucuronide isomers in normal men and women and in men infused with labeled dihydrotestosterone. | lld:pubmed |
| pubmed-article:3335605 | pubmed:affiliation | Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada. | lld:pubmed |
| pubmed-article:3335605 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3335605 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3335605 | lld:pubmed |
