Linked Life Data

3332873

Source:http://linkedlifedata.com/resource/pubmed/id/3332873

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-1-26
pubmed:abstractText
The presence of ring chromosomes is a rare finding in patients with de novo acute nonlymphocytic leukemia (ANLL). In this report we describe the cytogenetic abnormalities, including ring chromosomes, of a 45-year-old white male who had ANLL of the myelomonocytic type (M4). All of the leukemic cells had both a small unidentified ring and a medium-sized ring which was derived from chromosomes 2 and 11, r(2;11)(2p25;11p15q23;2q37). Four different types of rings or other structural abnormalities were derived from this medium-sized ring. A review of the literature indicated that the median survival of ANLL patients with either identified or unidentified ring chromosomes was 5 to 6 months, and that the presence of these cytogenetic abnormalities was related to a poor prognosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0886-0238
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
57-65
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Ring chromosome in a case of acute myelomonocytic leukemia: its significance and a review of the literature.
pubmed:affiliation
Cytogenetic Oncology Section, NCI, Bethesda, Maryland 20892.
pubmed:publicationType
Journal Article, Review, Case Reports