Linked Life Data

3330577

Source:http://linkedlifedata.com/resource/pubmed/id/3330577

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1988-7-18
pubmed:abstractText
Clinical evidence indicates that infection is still a cause of morbidity and mortality in patients undergoing hemodialysis. The major role played by the polymorphonuclear cells in antimicrobial response by the host explained considerable study of several aspects of granulocyte functions in chronic hemodialysis patients. It is now well documented that hemodialysis induces the sequential activation of the complement components of the alternative pathway and may provide a mechanism for initiating leukoaggregation and sequestration of granulocytes. This complement activation could also explain the profound leukopenia observed shortly after the initiation of hemodialysis. It has been also assumed that the sequestration of granulocytes is dependent on a temporarily altered cell function and leads to a depressed chemotaxis, an impairment of phagocytic and bactericidal capacities. Moreover, a significant defect in the oxidative metabolism was observed before and during the course of the dialysis session. This article summarizes research that has been done on the function of neutrophils from chronic hemodialysis patients.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0250-4960
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
287-92
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
[Functions and metabolism of polynuclear neutrophils in patients under chronic hemodialysis].
pubmed:affiliation
Laboratoire de Biochimie A, Hôpital Cochin, Paris.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract, Review