Linked Life Data

3329710

Source:http://linkedlifedata.com/resource/pubmed/id/3329710

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-6-14
pubmed:abstractText
Recombinant retroviruses encoding a murine c-myc gene were utilised to explore the consequences of constitutive c-myc expression for interleukin 3-dependent murine myeloid cell lines. The c-myc virus-infected cells exhibited a diminished requirement for growth factor and serum when grown in soft agar, but no factor-independent cells could be isolated and the cells were not tumorigenic. Thus deregulated expression of a c-myc gene at physiological levels apparently renders myeloid cells more responsive to growth factors but cannot abrogate this requirement or render the cells malignant.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0890-6467
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
61-76
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Murine c-myc retroviruses alter the growth requirements of myeloid cell lines.
pubmed:affiliation
Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Victoria, Australia.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't