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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1988-5-6
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pubmed:abstractText |
Using fluorescence histochemistry, we have examined the origin of noradrenaline (NA)-, 5-hydroxytryptamine (5-HT)- and neuropeptide Y (NPY)-containing perivascular nerve fibres supplying the major cerebral arteries of the gerbil, and the effect of superior cervical ganglionectomy on their cerebrovascular density and distribution. Bilateral ganglionectomy resulted in a complete loss of these perivascular nerve types in the anterior circulation, while a few fibres still persisted in the posterior circulatory bed. In addition, we demonstrate the presence of both 5-HT- and NPY-positive cell bodies in the superior cervical ganglion (SCG) of adult gerbils, suggesting that the main origin of cerebrovascular 5-HT- and NPY- (as well as NA-) containing nerve fibres is in the SCG.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0393-5264
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
417-20
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:3327766-Animals,
pubmed-meshheading:3327766-Blood Vessels,
pubmed-meshheading:3327766-Cerebrovascular Circulation,
pubmed-meshheading:3327766-Fluorescent Antibody Technique,
pubmed-meshheading:3327766-Histocytochemistry,
pubmed-meshheading:3327766-Immunohistochemistry,
pubmed-meshheading:3327766-Nerve Fibers,
pubmed-meshheading:3327766-Neuropeptide Y,
pubmed-meshheading:3327766-Norepinephrine,
pubmed-meshheading:3327766-Serotonin,
pubmed-meshheading:3327766-Sympathectomy
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pubmed:articleTitle |
Histochemical and immunohistochemical study of noradrenergic, serotonergic and peptidergic innervation of the cerebral circulation.
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pubmed:affiliation |
Department of Anatomy and Developmental Biology, University College London, United Kingdom.
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pubmed:publicationType |
Journal Article
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