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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1988-4-4
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pubmed:abstractText |
A protein corresponding in size to the bcl-2 alpha protein obtained after in vitro transcription and in vitro translation in a rabbit reticulocyte lysate was specifically immunoprecipitated from a human B-cell extract using rabbit polyclonal antiserum raised against a beta-galactosidase/bcl-2 fusion protein. Peptide mapping with V8 protease confirmed the identity of this protein as human bcl-2 alpha. Subcellular fractionation of cellular protein followed by immunoprecipitation showed that the bcl-2 alpha protein is associated with the cell membrane.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0950-9232
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3325884-B-Lymphocytes,
pubmed-meshheading:3325884-Cell Compartmentation,
pubmed-meshheading:3325884-Cloning, Molecular,
pubmed-meshheading:3325884-DNA, Neoplasm,
pubmed-meshheading:3325884-Genes,
pubmed-meshheading:3325884-Humans,
pubmed-meshheading:3325884-Immunologic Techniques,
pubmed-meshheading:3325884-Lymphoma,
pubmed-meshheading:3325884-Membrane Proteins,
pubmed-meshheading:3325884-Peptide Mapping,
pubmed-meshheading:3325884-Proto-Oncogene Proteins,
pubmed-meshheading:3325884-Recombinant Fusion Proteins,
pubmed-meshheading:3325884-Translocation, Genetic
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pubmed:year |
1987
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pubmed:articleTitle |
Characterization of the protein product of bcl-2, the gene involved in human follicular lymphoma.
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pubmed:affiliation |
Wistar Institute, Philadelphia 19104.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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