Linked Life Data

3322838

Source:http://linkedlifedata.com/resource/pubmed/id/3322838

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1988-3-3
pubmed:abstractText
Eleven patients suffering from idiopathic Parkinson's disease participated in an open study of Madopar HBS. At the beginning the patients were switched from standard Madopar to Madopar HBS, initially keeping constant L-dopa dosage and the number of daily doses. In 9 of the 11 patients a marked deterioration occurred within a few days. In spite of increasing the daily dosage of L-dopa the condition remained unsatisfactory in several patients and forced us to prematurely discontinue the study in 5 cases. The Webster ratings improved in 1 patient, remained unchanged in 4 cases and a definite worsening occurred in 6 patients. Fluctuations of the symptomatology were improved in none of our patients. It is not excluded that these negative results might have been improved by a further increase of Madopar HBS, a less abrupt switch from standard Madopar to Madopar HBS and probably also a combination of the two forms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0014-3022
pubmed:author
pubmed:issnType
Print
pubmed:volume
27 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
73-5
pubmed:dateRevised
2009-12-23
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Open clinical study of Madopar HBS.
pubmed:affiliation
Neurological Clinic, University of Berne, Switzerland.
pubmed:publicationType
Journal Article, Clinical Trial