Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1977-10-31
pubmed:abstractText
Although nickel is an essential element for animal nutrition, the physiological role of nickel is not yet established. Pathological alterations of nickel metabolism are recognized in several human diseases. The diverse clinical manifestations of nickel toxicology include: (1) acute pneumonitis from inhalation of nickel carbonyl, (2) chronic rhinitis and sinusitis from inhalation of nickel aerosols, (3) cancers of nasal cavities and lungs in nickel workers, and (4) dermatitis and other hypersensitive reactions from cutaneous and parenteral exposures to nickel alloys. The toxicity, carcinogenicity and embryotoxicity of nickel compounds in experimental animals are reviewed in this article, and consideration is given to the therapeutic use of chelating drugs in nickel poisoning.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0091-7370
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
377-98
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:332046-Abnormalities, Drug-Induced, pubmed-meshheading:332046-Adult, pubmed-meshheading:332046-Connecticut, pubmed-meshheading:332046-Dermatitis, Atopic, pubmed-meshheading:332046-Environmental Exposure, pubmed-meshheading:332046-Female, pubmed-meshheading:332046-Humans, pubmed-meshheading:332046-Hyperglycemia, pubmed-meshheading:332046-Kidney, pubmed-meshheading:332046-Liver, pubmed-meshheading:332046-Lung, pubmed-meshheading:332046-Male, pubmed-meshheading:332046-Neoplasms, Experimental, pubmed-meshheading:332046-Nickel, pubmed-meshheading:332046-Nutritional Requirements, pubmed-meshheading:332046-Occupational Diseases, pubmed-meshheading:332046-Polycythemia, pubmed-meshheading:332046-Pregnancy, pubmed-meshheading:332046-Protein Binding, pubmed-meshheading:332046-Respiratory Tract Neoplasms
pubmed:articleTitle
A review of the metabolism and toxicology of nickel.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Case Reports