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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1988-2-24
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pubmed:abstractText |
The incidence of Syrian golden hamsters with pancreatic cancer induced by subcutaneous injections of N-nitroso-bis(2-oxopropyl)amine for 19 weeks (each 10 mg/kg) increased from 44% to 75% (p=0.016) when epidermal growth factor was also administered from week 5 through week 8 (5 mug energy three days for injections). Epidermal growth factor increased pancreatic weight and body weight. The incidence of animals with bronchial cancer doubled. Epidermal growth factor could be a cocarcinogen as a result of its mitogenic activity.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-221755,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-2417223,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-2420792,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-2857131,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-2994064,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-2997917,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-3001700,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-3002607,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-3002608,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-3009003,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-3697980,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-3753985,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-3871506,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-3873715,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-3883191,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-3966964,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-468958,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-6200216,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-6320011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-6456057,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-6538696,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-6640529,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-6692105,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-6848182,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-7089870,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-7471075,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3319811-954982
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0017-5749
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
28 Suppl
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
249-51
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1987
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pubmed:articleTitle |
Augmentation of chemically induced pancreatic and bronchial cancers by epidermal growth factor.
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pubmed:affiliation |
Surgical Services, Shriners Burns Institute, Mass
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pubmed:publicationType |
Journal Article
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