Linked Life Data

3318966

Source:http://linkedlifedata.com/resource/pubmed/id/3318966

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-2-17
pubmed:abstractText
The object of the study was to find a model to summarize all the information from dose-response curves, by determining the coefficients to be used to compare groups of subjects. Three coefficients were calculated from the following model: F(d)/F(o) = ONE - k(d-delta)alpha+, where F(d)/F(o) was the ratio between FEV1 at dose (d) of methacholine and prechallenge FEV1, 'k' the slope of the relative variation of FEV1 with the dose, 'delta' the threshold dose and 'alpha' a shape factor. The model was applied to the study of hyperresponsiveness in a population of 317 men. The results illustrated the interest of this model which was applicable to 91% of the population and permitted fine discrimination of the groups studied.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0395-3890
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
383-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Analysis of the methacholine dose-response curve: usefulness of a simplified log-logistic model in epidemiological studies.
pubmed:affiliation
INSERM U 179, Le Vésinet, France.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't