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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1987-12-14
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pubmed:abstractText |
To find a rapid and sensitive test for detection of Group A streptococci (GABS), the performance of the TestPack Strep A (TPSA; Abbott) was compared with culture with the use of rayon-tipped throat swabs from symptomatic patients six months to 90 years of age. Each swab was first inoculated to a 5% sheep blood agar plate and then tested for GABS antigen with the use of the TPSA and the manufacturer's instructions. Cultures were incubated anaerobically at 35 degrees C for 36-48 hours unless positive results were obtained after one night. GABS were identified with a fluorescent antibody method or a latex antibody test. From 1,616 throat swabs, 296 (18.3%) of the cultures contained GABS. The sensitivity and specificity of the TPSA were 73.3% and 94.8%, respectively, whereas the predictive values of positive and negative results were 75.9% and 94.1%, respectively. Results varied significantly, however, with different production lots of TPSA. The TPSA does not appear to provide a sensitive alternative to an anaerobic culture for detection of GABS.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0002-9173
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
631-4
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3314472-Adolescent,
pubmed-meshheading:3314472-Adult,
pubmed-meshheading:3314472-Aged,
pubmed-meshheading:3314472-Aged, 80 and over,
pubmed-meshheading:3314472-Child,
pubmed-meshheading:3314472-Child, Preschool,
pubmed-meshheading:3314472-Evaluation Studies as Topic,
pubmed-meshheading:3314472-Humans,
pubmed-meshheading:3314472-Immunoenzyme Techniques,
pubmed-meshheading:3314472-Infant,
pubmed-meshheading:3314472-Methods,
pubmed-meshheading:3314472-Middle Aged,
pubmed-meshheading:3314472-Oropharynx,
pubmed-meshheading:3314472-Pharyngitis,
pubmed-meshheading:3314472-Reagent Kits, Diagnostic,
pubmed-meshheading:3314472-Streptococcus pyogenes
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pubmed:year |
1987
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pubmed:articleTitle |
Comparison of the TestPack Strep A enzyme immunoassay system with anaerobically incubated cultures for detection of group A streptococci from oropharyngeal swabs.
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pubmed:affiliation |
Clinical Microbiology Laboratory, York Hospital, Pennsylvania 17405.
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pubmed:publicationType |
Journal Article,
Comparative Study
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