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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1987-12-11
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pubmed:abstractText |
In a prospective randomized placebo controlled double blind study, the prophylactic effect of mesalazine (5-aminosalicylic acid. 5-ASA) as suppositories (3 x 250 mg/day) on radiation induced proctitis during radiotherapy for prostatic carcinoma was studied. The study ended when 16 patients had been included (5-ASA: eight, placebo: eight) because of severe side effects in the 5-ASA group. 75% of patients treated with 5-ASA reported symptoms of a severe proctitis while only one patient in the placebo group had similar complaints. The application of mesalazine as suppositories is not useful in preventing radiation induced proctitis during radiotherapy of prostate carcinoma.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0179-7158
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
163
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
678-80
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3313776-Aged,
pubmed-meshheading:3313776-Aged, 80 and over,
pubmed-meshheading:3313776-Aminosalicylic Acids,
pubmed-meshheading:3313776-Clinical Trials as Topic,
pubmed-meshheading:3313776-Double-Blind Method,
pubmed-meshheading:3313776-Humans,
pubmed-meshheading:3313776-Male,
pubmed-meshheading:3313776-Mesalamine,
pubmed-meshheading:3313776-Middle Aged,
pubmed-meshheading:3313776-Proctitis,
pubmed-meshheading:3313776-Prospective Studies,
pubmed-meshheading:3313776-Prostatic Neoplasms,
pubmed-meshheading:3313776-Radiation Injuries,
pubmed-meshheading:3313776-Radiation-Protective Agents,
pubmed-meshheading:3313776-Radiotherapy,
pubmed-meshheading:3313776-Random Allocation,
pubmed-meshheading:3313776-Suppositories,
pubmed-meshheading:3313776-Time Factors
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pubmed:year |
1987
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pubmed:articleTitle |
[Unwanted side-effects in using mesalazine (5-aminosalicylic acid) during radiotherapy].
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pubmed:affiliation |
Abteilung Röntgen- und Strahlentherapie, Universitätsklinik Freiburg.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract,
Randomized Controlled Trial
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