Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1987-11-20
pubmed:abstractText
The physiological variations in serum TSH concentration have been investigated using an enzyme amplified immunoassay with improved sensitivity and precision. Blood samples were collected at regular intervals from 10 healthy volunteers during the period 1800 h to 0100 h. Spectral analysis followed by periodic regression analysis demonstrated significant serum TSH pulsatility with periodicities of 60 or 85-100 min. In addition, a significant (P less than 0.001) evening rise in serum TSH concentration was demonstrated in all subjects, with levels rising at around 21.30-22.00 h.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0004-5632
pubmed:author
pubmed:issnType
Print
pubmed:volume
24 ( Pt 5)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
470-6
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Pulsatile secretion of TSH in healthy subjects.
pubmed:affiliation
Department of Clinical Biochemistry, Addenbrooke's Hospital, Cambridge, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't