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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1987-11-12
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pubmed:abstractText |
In an attempt to define the early features and the natural evolution of lung involvement in progressive systemic sclerosis (PSS), we planned a multidisciplinary study of these patients using radiological, scintigraphic and functional methods. As yet we have studied 21 subjects, all affected by PSS according to the American Rheumatism Association criteria. A well-defined restrictive functional pattern was present only in 10 patients out of 21; an increased elastic recoil may be present before a significant decrease of the transfer test for carbon monoxide; an increased alveolar-capillary permeability assessed by the 99mTc-diethylene-triamine-pentacetic acid (99mTc-DTPA) clearance rate has been detected in almost all the patients (13 out of 14) in at least one lung field; no significant correlation has been found between the radiological lung involvement and the 99mTc-DTPA clearance rate. We think that these preliminary results are consistent with an alveolar and interstitial inflammation rather than with a vasculitic process.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0025-7931
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
296-306
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:3310160-Adult,
pubmed-meshheading:3310160-Child,
pubmed-meshheading:3310160-Female,
pubmed-meshheading:3310160-Humans,
pubmed-meshheading:3310160-Lung,
pubmed-meshheading:3310160-Male,
pubmed-meshheading:3310160-Middle Aged,
pubmed-meshheading:3310160-Organometallic Compounds,
pubmed-meshheading:3310160-Pentetic Acid,
pubmed-meshheading:3310160-Respiratory Function Tests,
pubmed-meshheading:3310160-Scleroderma, Systemic,
pubmed-meshheading:3310160-Technetium Tc 99m Pentetate
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pubmed:year |
1987
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pubmed:articleTitle |
Pulmonary involvement in progressive systemic sclerosis: a multidisciplinary approach.
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pubmed:affiliation |
Istituto di Clinica Medica, Università Cattolica S. Cuore, Roma, Italy.
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pubmed:publicationType |
Journal Article
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