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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1987-10-15
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pubmed:abstractText |
Endotoxin (LPS) and radio-detoxified endotoxin (RD-LPS: 150 kGy 60Co-gamma irradiated) preparations were compared in mice (C57Bl X CBA: F1/Rapo) for capacity to enhance the immune response against sheep red blood cells and to induce the production of antibody against autologous (bromelain-treated) erythrocytes. As RD-LPS retains its capacity to stimulate immune response against heterologous antigen, it may be used as an immuno-adjuvant. The LPS preparation gave rise to a significant increase of autoreactive cells. However, RD-LPS activated the autoantibody forming cells only to a very small degree.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0231-4622
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
33
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
311-5
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pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3307274-Adjuvants, Immunologic,
pubmed-meshheading:3307274-Animals,
pubmed-meshheading:3307274-Autoantibodies,
pubmed-meshheading:3307274-Endotoxins,
pubmed-meshheading:3307274-Erythrocytes,
pubmed-meshheading:3307274-Escherichia coli,
pubmed-meshheading:3307274-Lipopolysaccharides,
pubmed-meshheading:3307274-Male,
pubmed-meshheading:3307274-Mice
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pubmed:year |
1986
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pubmed:articleTitle |
Comparison of adjuvanticity and autoantibody inducing capacity of endotoxin and radio-detoxified endotoxin in mice.
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pubmed:publicationType |
Journal Article,
Comparative Study
|