Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1987-9-30
pubmed:abstractText
We examined the capacity of hearts injured during 24 hours of preservation to recover function over 96 hours when placed in an ectopic transplant configuration. Standard Langendorff techniques employing an intraventricular balloon and fixed perfusion pressure of 80 mm Hg were used to measure parameters of myocardial function, including maximal systolic pressure, left ventricular end diastolic pressure, and left ventricular balloon volume. Hearts preserved for 24 hours and held ischemic for 1 hour at room temperature exhibited significantly depressed contractility (maximal systolic pressure decreased by 26%) and diastolic compliance (left ventricular balloon volume decreased by 61%). During 96 hours in the ectopic transplant configuration, 24-hour preserved hearts recovered 52% of the lost diastolic compliance. These data demonstrate that 24-hour preserved and transplanted hearts recovered function over 96 hours.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0887-2570
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
298-303
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Recovery of heart function following 24 hours preservation and ectopic transplantation.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't