Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1987-9-14
|
pubmed:abstractText |
Rabbits were injected intravitreally with colchicine and the retinas were subsequently processed for simultaneous visualization of GAD-like and GABA-like immunoreactivity (LIR) at the light microscopical level. The use of specific antisera from unrelated species minimized the possibility of crossreactivity between the two markers. Colocalization of GABA-LIR and GAD-LIR was observed in approximately 32% of somata on the inner border of the inner nuclear layer (INL) and roughly 15% of the somata in the ganglion cell layer (GCL). All GAD-positive cells were double labeled whereas 15% of the GABA-LIR cells in the INL and 52% of those in the GCL were negative for GAD-LIR. Both markers were seen throughout the inner plexiform layer. In addition, processes coursing through the OPL, perhaps from interplexiform cells, and horizontal cell bodies were double-labeled with these GABAergic probes.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0042-6989
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
27
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
23-30
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:3303678-Animals,
pubmed-meshheading:3303678-Cross Reactions,
pubmed-meshheading:3303678-Fluorescent Antibody Technique,
pubmed-meshheading:3303678-Glutamate Decarboxylase,
pubmed-meshheading:3303678-Immune Sera,
pubmed-meshheading:3303678-Rabbits,
pubmed-meshheading:3303678-Retina,
pubmed-meshheading:3303678-Retinal Ganglion Cells,
pubmed-meshheading:3303678-gamma-Aminobutyric Acid
|
pubmed:year |
1987
|
pubmed:articleTitle |
Double-label analysis of GAD- and GABA-like immunoreactivity in the rabbit retina.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
|