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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1987-8-28
|
| pubmed:abstractText |
A study of the effects of oral acyclovir (200 mg), administered five times per day for 5 days in 210 patients who cultured positive for herpes labialis, is made. A total of 149 patients were followed through three episodes each of herpes labialis while taking a placebo or acyclovir. Patients were evaluated for several clinical parameters, including the loss of lesion crust and reduction of the size of the area of the lesion between day 1 and day 5. Acyclovir showed a significant antiviral effect. Results show that oral acyclovir can favorably affect some parameters, but that higher doses or a "loading dose" could improve its efficacy.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
D
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0002-8177
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
115
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
38-42
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3301980-Acyclovir,
pubmed-meshheading:3301980-Administration, Oral,
pubmed-meshheading:3301980-Adult,
pubmed-meshheading:3301980-Clinical Trials as Topic,
pubmed-meshheading:3301980-Double-Blind Method,
pubmed-meshheading:3301980-Drug Administration Schedule,
pubmed-meshheading:3301980-Female,
pubmed-meshheading:3301980-Herpes Labialis,
pubmed-meshheading:3301980-Humans,
pubmed-meshheading:3301980-Male,
pubmed-meshheading:3301980-Middle Aged,
pubmed-meshheading:3301980-Patient Compliance,
pubmed-meshheading:3301980-Random Allocation
|
| pubmed:year |
1987
|
| pubmed:articleTitle |
Oral acyclovir and herpes labialis: a randomized, double-blind, placebo-controlled study.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|