Linked Life Data

3301032

Source:http://linkedlifedata.com/resource/pubmed/id/3301032

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1987-9-2
pubmed:abstractText
The parasite-burden, which is indicative of the macrophage activity, was determined before treatment in 84 kala azar cases (L. infantum) and compared to non specific immune response parameters (serum IgG, and IgM), to the specific antibody levels as detected by immunofluorescence and IgG and IgM-ELISA, as well as to rheumatoid factor titers. In 57 cases presenting with less than 3 months from the first appearance of symptoms and despite some individual variations, high parasite-burden levels were accompanied with high specific and non specific immune response parameters and inversely. The data suggest that, during kala azar, low and high immune responders could be distinguished in the humans in the way it was demonstrated by Biozzi in mice. Data collected from 27 cases with more than 3 months duration showed a poor correlation. However, at highest antibody levels, some decreasing in parasite-burden was noticed. The prognostic value of the parasite-burden determination is emphasized. Genetic studies of populations would improve control measures.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0037-9085
pubmed:author
pubmed:issnType
Print
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
218-29
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
[Parasite burden and immune response in kala-azar].
pubmed:publicationType
Journal Article, English Abstract