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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3-4
|
| pubmed:dateCreated |
1987-8-18
|
| pubmed:abstractText |
Various patterns of mouse pancreatic proteinase activity bands were observed on agarose gel electrophoresis. Prt-1a and Prt-1b genes control the positive (PRT-1A) and negative (PRT-1B) expression of tryptic band V, respectively; Prt-2a and Prt-2b correspond to chymotryptic bands II (PRT-2A) and III (PRT-2B); Prt-3a and Prt-3b control the low (PRT-3A) and high (PRT-3B) tryptic activities of band IV; the Prt-1 and Prt-3 loci are closely linked on the same chromosome; Prt-6a and Prt-6b correspond to tryptic bands I (PRT-6A) and I' (PRT-6B). Twenty-four laboratory strains from the United States showed the phenotype PRT-1A, PRT-3A, and PRT-2A. Of laboratory strains established in Europe, 6 showed PRT-1A, PRT-3A, and PRT-2A, and 10 had PRT-1B, PRT-3A, and PRT-2A bands. Most wild mice around the world and their descendants showed the phenotype PRT-1B, PRT-3B, and PRT-2A. Only the phenotype of M. m. brevirostris was PRT-1A, PRT-3A, and PRT-2A, which was the same as most laboratory inbred strains. PRT-2B was observed mainly in Japanese (M.m. molossinus) and Korean (M.m. yamashinai) wild mice. PRT-6B was detected only in Mus spicilegus and Mus caroli, but all other mice including wild populations and laboratory strains showed PRT-6A. New biochemical phenotypes such as PRT-2C and PRT-3C were also found in this study.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0006-2928
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
25
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
239-51
|
| pubmed:dateRevised |
2010-11-18
|
| pubmed:meshHeading |
pubmed-meshheading:3300637-Alleles,
pubmed-meshheading:3300637-Animals,
pubmed-meshheading:3300637-Biological Evolution,
pubmed-meshheading:3300637-Chymotrypsin,
pubmed-meshheading:3300637-Electrophoresis, Agar Gel,
pubmed-meshheading:3300637-Endopeptidases,
pubmed-meshheading:3300637-Mice,
pubmed-meshheading:3300637-Pancreas,
pubmed-meshheading:3300637-Phenotype,
pubmed-meshheading:3300637-Species Specificity,
pubmed-meshheading:3300637-Trypsin
|
| pubmed:year |
1987
|
| pubmed:articleTitle |
Evolutionary relationships between laboratory mice and subspecies of Mus musculus based on the genetic study of pancreatic proteinase loci, Prt-1, Prt-2, Prt-3, and Prt-6.
|
| pubmed:publicationType |
Journal Article
|