Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1987-8-11
pubmed:abstractText
We used monospecific antibodies on semithin frozen sections to identify and localize the major tissue constituents of the nonglaucomatous human trabecular meshwork. The trabecular beams (sheets and cords) consist of a basement membrane (subendothelial extracellular matrix) surrounding an interstitial central core of connective tissue (substantia propria). The basement membrane contains collagen types III, IV, and V, the glycoproteins laminin and fibronectin, and the basement membrane-associated heparan sulfate proteoglycan. The trabecular basement membrane is unlike most subendothelial basement membranes because it contains collagen type III and a relatively disorganized structure. The central core contains collagen types I and III, and elastin. The closely linked juxtacanalicular meshwork contains collagen type III, but no collagen type I or elastin. The connective tissue composition of the trabecular meshwork appears similar to other highly compliant and resilient tissues, such as lung, blood vessels, and conjunctiva.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0002-9394
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
104
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
33-43
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Localization of extracellular proteins of the human trabecular meshwork by indirect immunofluorescence.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't