Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1977-10-14
pubmed:abstractText
A Short Review is given of the biochemical neurotoxic mechanisms of common industrial solvents of various structures. The acute effects of organic solvents may be caused by their direct action on the nerve cell membrane and energy metabolism, whereas chronic neurotoxic effects may be explained by the formation of chemically and biologically reactive intermediates. The stability of the toxic metabolites appears to correlate with the development of neuropathy although this is structuredependent. The role of reactive intermediates is also emphasized by the potentiating effect of the induction of the cytochrome P-450 complex.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0009-2797
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-10
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Some aspects of the mechanisms by which industrial solvents produce neurotoxic effects.
pubmed:publicationType
Journal Article, Review