Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1988-8-31
pubmed:abstractText
A monoclonal antibody, 14E, which detects immunocytochemically the perikarya of interfascicular oligodendrocytes in sections of normal adult human and rat white matter, was obtained using isolated normal human oligodendrocytes as the immunogen. 14E is an IgM antibody that reacts with a polypeptide of approximate molecular weight 23,000 on immunoblots of the particulate fraction of normal white matter. In sections of active multiple sclerosis plaques and recent infarcts, 14E immunostained the cell bodies and processes of only a small number of hypertrophic glial cells which could be oligodendrocytes undergoing pathological changes or a subpopulation of reactive astrocytes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0165-5728
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
11-20
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Monoclonal antibody 14E identifies the oligodendrocyte cell body in normal adult human and rat white matter.
pubmed:affiliation
Department of Neurochemistry, Institute of Neurology, London, U.K.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't