Linked Life Data

3293792

Source:http://linkedlifedata.com/resource/pubmed/id/3293792

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-9-7
pubmed:abstractText
Protein antigens accumulated in the oocyte nucleus of Xenopus spp. are found later in all nuclei of the embryo. During and after organogenesis, the fate of different nuclear antigens diverges: Some are permanently expressed in all nuclei, some are no longer detectable in any nuclei, and some show a high degree of specificity relative to cell type. Of the class of antigens permanently expressed in all cells, a nucleolar antigen has been studied that is relatively enriched in the gonia of both sexes. A possible correlations of its occurrence with ribosomal DNA amplification and transcription is examined. The cell-specific expression of 4 antigens has been analyzed in detail, using indirect immunofluorescent staining methods as well as conventional histology. The tissue-specificity of 2 of these antigens does not change during metamorphosis, whereas the pattern of others is dynamic until after metamorphosis. We conclude that the observed tissue-specificity does not correlate with descendence from one of the 3 primary germ layers: Some antigens appear to accumulate in the nucleus when a cell takes up its specific function.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0302-766X
pubmed:author
pubmed:issnType
Print
pubmed:volume
252
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
479-89
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Cell specificity of nuclear protein antigens in the development of Xenopus species.
pubmed:affiliation
Max-Planck-Institut für Entwicklungsbiologie, Abteilung für Zellbiologie, Tübingen, Federal Republic of Germany.
pubmed:publicationType
Journal Article