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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6177
|
pubmed:dateCreated |
1988-8-8
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pubmed:abstractText |
Saccharomyces cerevisiae contains a protein which is functionally similar to the mammalian TATA element-binding transcription factor, TFIID. The yeast factor substitutes for TFIID in a mammalian RNA polymerase II in vitro transcription system, forms a stable preinitiation complex on the Adenovirus-2 major late promoter, and binds specifically to the TATA boxes of the viral promoter and the yeast CYC1 promoter. Interestingly, the yeast factor promotes initiation at a distance from the TATA element typical of a mammalian system.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0028-0836
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
334
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
37-42
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:3290687-DNA-Binding Proteins,
pubmed-meshheading:3290687-HeLa Cells,
pubmed-meshheading:3290687-Humans,
pubmed-meshheading:3290687-Peptide Chain Initiation, Translational,
pubmed-meshheading:3290687-Promoter Regions, Genetic,
pubmed-meshheading:3290687-RNA Polymerase II,
pubmed-meshheading:3290687-Regulatory Sequences, Nucleic Acid,
pubmed-meshheading:3290687-Saccharomyces cerevisiae,
pubmed-meshheading:3290687-Species Specificity,
pubmed-meshheading:3290687-Transcription, Genetic,
pubmed-meshheading:3290687-Transcription Factors
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pubmed:year |
1988
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pubmed:articleTitle |
Function of a yeast TATA element-binding protein in a mammalian transcription system.
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pubmed:affiliation |
Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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