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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1988-7-8
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pubmed:abstractText |
In a randomized multicenter study, ciprofloxacin and norfloxacin, each in two different dose regimens and in combination with non-absorbable antimycotics, were administered to 51 patients with acute leukaemia undergoing aggressive remission induction chemotherapy for infection prevention. Both drugs showed an effective elimination of gram-negative potential pathogens and Staphylococcus aureus not affecting the anaerobic flora of the gastrointestinal tract. A low incidence of side effects and a satisfactory patient compliance could be observed. A daily dosage of 1,000 mg ciprofloxacin or 800 mg norfloxacin is recommended for infection prevention in severely granulocytopenic patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-8126
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
98-104
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3286509-Acute Disease,
pubmed-meshheading:3286509-Adult,
pubmed-meshheading:3286509-Agranulocytosis,
pubmed-meshheading:3286509-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:3286509-Bacterial Infections,
pubmed-meshheading:3286509-Ciprofloxacin,
pubmed-meshheading:3286509-Clinical Trials as Topic,
pubmed-meshheading:3286509-Humans,
pubmed-meshheading:3286509-Leukemia,
pubmed-meshheading:3286509-Norfloxacin,
pubmed-meshheading:3286509-Pilot Projects,
pubmed-meshheading:3286509-Random Allocation,
pubmed-meshheading:3286509-Remission Induction
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pubmed:articleTitle |
Ciprofloxacin and norfloxacin for selective decontamination in patients with severe granulocytopenia.
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pubmed:affiliation |
Department of Internal Medicine, Haematology and Oncology, Evangelisches Krankenhaus, Essen-Werden.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|