Linked Life Data

328446

Source:http://linkedlifedata.com/resource/pubmed/id/328446

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1977-9-29
pubmed:abstractText
Antinuclear antibodies (ANA) were examined in the sera of 28 patients with chronic open angle glaucoma (COAG) and 24 normal volunteers by an immunoperoxidase technique. Unlike the results of a previous report, no significant difference in titers was found between the two groups. A highly objective radioimmunoassay for DNA antibody was also employed, giving similar results. The increased incidence of ANA at low dilutions in both COAG and normal groups in this study and its absence when measured by radioimmunoassay suggest that positive ANA reactions at such low dilutions are the result of nonspecific binding. The lack of demonstrable differences from normal in ANA- or DNA-binding antibody does not support the results of earlier studies suggesting a humoral immune or autoimmune mechanism in COAG.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0146-0404
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
757-60
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
A comparison of antinuclear antibodies and DNA-binding antibodies in chronic open-angle glaucoma.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.