Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-5-27
pubmed:abstractText
The proliferative activity and growth pattern of 20 seminomas were determined immunohistologically with the monoclonal antibody Ki-67. A growth fraction of tumour cells between 50 and 80% was found in seminomas with an almost even distribution of proliferating cells in all sections, regardless of tumour size. There was a slight tendency towards a greater growth fraction in tumours at an advanced histopathological stage. No positive correlation could be found between growth fraction and tumour size or lymphocytic infiltration. The results confirm the well known sensitivity of seminomas to radiation and chemotherapy and show that the determination of proliferative activity should be included in the histopathological routine diagnosis of malignant tumours with regard to systemic treatment and prognosis.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-1098765, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-13042768, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-2409348, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-2428460, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-2579727, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-3013945, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-3034789, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-3314057, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-3893507, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-3978564, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-3999091, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-402206, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-5965751, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-6154516, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-6158370, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-6198355, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-6206131, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-6208748, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-6985715, http://linkedlifedata.com/resource/pubmed/commentcorrection/3283173-7370929
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0021-9746
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
304-7
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Immunohistological determination of proliferative activity in seminomas.
pubmed:affiliation
Institute of Pathology, Free University, Berlin, West Germany.
pubmed:publicationType
Journal Article