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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1988-6-7
|
pubmed:abstractText |
Molecular biologic investigation of the process of immunoglobulin gene rearrangement has elucidated the mechanism of immunologic diversification and has provided essential tools for the study of B-cell neoplasia. The use of immunoglobulin gene probes has permitted a clearer understanding of B-cell malignancies, but has also raised new questions and pointed out new directions for ultimately clarifying the mechanism of B-cell transformation. Thus, we have a difficult challenge ahead, but with our present knowledge, we are in a better position than ever to address critical issues relating to the genesis of lymphoid neoplasia.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0272-2712
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
45-64
|
pubmed:dateRevised |
2006-3-28
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pubmed:meshHeading |
pubmed-meshheading:3282763-Animals,
pubmed-meshheading:3282763-B-Lymphocytes,
pubmed-meshheading:3282763-Cell Differentiation,
pubmed-meshheading:3282763-Genes, Immunoglobulin,
pubmed-meshheading:3282763-Genes, Switch,
pubmed-meshheading:3282763-Humans,
pubmed-meshheading:3282763-Leukemia,
pubmed-meshheading:3282763-Lymphoma
|
pubmed:year |
1988
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pubmed:articleTitle |
Immunoglobulin gene rearrangement and its implications for the study of B-cell neoplasia.
|
pubmed:affiliation |
University of Texas System Cancer Center, Houston.
|
pubmed:publicationType |
Journal Article,
Review
|