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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1988-5-25
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pubmed:abstractText |
To examine the efficacy of the monoamine oxidase inhibitor phenelzine sulfate in the treatment of bulimia, a double-blind, placebo-controlled trial was conducted. In 50 women who completed the trial, phenelzine was significantly superior to placebo in the reduction of binge frequency (64% vs 5%), in the fraction of patients who had ceased bingeing at the end of the trial (35% vs 4%), and in several measures of psychological state. The superiority of phenelzine over placebo was not confined to a depressed subgroup of patients. Although no patient experienced a hypertensive crisis during the study, other side effects of phenelzine were problematic and limit the usefulness of phenelzine in this population.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0003-990X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
471-5
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3282482-Adolescent,
pubmed-meshheading:3282482-Adult,
pubmed-meshheading:3282482-Bulimia,
pubmed-meshheading:3282482-Clinical Trials as Topic,
pubmed-meshheading:3282482-Depressive Disorder,
pubmed-meshheading:3282482-Double-Blind Method,
pubmed-meshheading:3282482-Female,
pubmed-meshheading:3282482-Humans,
pubmed-meshheading:3282482-Hypertension,
pubmed-meshheading:3282482-Middle Aged,
pubmed-meshheading:3282482-Outcome and Process Assessment (Health Care),
pubmed-meshheading:3282482-Phenelzine,
pubmed-meshheading:3282482-Placebos,
pubmed-meshheading:3282482-Psychiatric Status Rating Scales
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pubmed:year |
1988
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pubmed:articleTitle |
Phenelzine vs placebo in 50 patients with bulimia.
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pubmed:affiliation |
New York State Psychiatric Institute.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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