| pubmed-article:3281909 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3281909 | lifeskim:mentions | umls-concept:C0317812 | lld:lifeskim |
| pubmed-article:3281909 | lifeskim:mentions | umls-concept:C0080194 | lld:lifeskim |
| pubmed-article:3281909 | lifeskim:mentions | umls-concept:C0003339 | lld:lifeskim |
| pubmed-article:3281909 | lifeskim:mentions | umls-concept:C0205419 | lld:lifeskim |
| pubmed-article:3281909 | lifeskim:mentions | umls-concept:C0019409 | lld:lifeskim |
| pubmed-article:3281909 | lifeskim:mentions | umls-concept:C1521828 | lld:lifeskim |
| pubmed-article:3281909 | lifeskim:mentions | umls-concept:C0205164 | lld:lifeskim |
| pubmed-article:3281909 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:3281909 | pubmed:dateCreated | 1988-5-26 | lld:pubmed |
| pubmed-article:3281909 | pubmed:abstractText | Monoclonal and monospecific antibodies were used to characterize a major Mycoplasma pulmonis surface antigen complex, V-1. Heterogeneity of V-1 was detected among strains and a high frequency of variation was detected within subclones of single strains. Analysis of 18 different strains showed that no two displayed identical electrophoretic immunoblot patterns for V-1. Analysis of 50 filter clones from an individual strain (not previously filter cloned) revealed at least 10 different V-1 patterns. The two most frequently occurring patterns were expressed by 36% and 24%, respectively, of the total population. Serial subcloning (four separate series) of several of these original clones showed that the average rate of V-1 variation was 2 x 10(-3) per cell per generation. Immunoblots with different anti-V-1 monoclonal antibodies demonstrated that there were both structurally and antigenically different forms of this antigen. Also, two-dimensional polyacrylamide gel analyses showed that different forms of V-1 could vary in charge. This potential for variability in a major surface antigen of mycoplasmas could have important implications as to how the organism interacts with its host. | lld:pubmed |
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| pubmed-article:3281909 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3281909 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3281909 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:3281909 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3281909 | pubmed:month | May | lld:pubmed |
| pubmed-article:3281909 | pubmed:issn | 0019-9567 | lld:pubmed |
| pubmed-article:3281909 | pubmed:author | pubmed-author:CassellG HGH | lld:pubmed |
| pubmed-article:3281909 | pubmed:author | pubmed-author:McDanielL SLS | lld:pubmed |
| pubmed-article:3281909 | pubmed:author | pubmed-author:WatsonH LHL | lld:pubmed |
| pubmed-article:3281909 | pubmed:author | pubmed-author:BlalockD KDK | lld:pubmed |
| pubmed-article:3281909 | pubmed:author | pubmed-author:FallonM TMT | lld:pubmed |
| pubmed-article:3281909 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3281909 | pubmed:volume | 56 | lld:pubmed |
| pubmed-article:3281909 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3281909 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3281909 | pubmed:pagination | 1358-63 | lld:pubmed |
| pubmed-article:3281909 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:3281909 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3281909 | pubmed:articleTitle | Heterogeneity among strains and a high rate of variation within strains of a major surface antigen of Mycoplasma pulmonis. | lld:pubmed |
| pubmed-article:3281909 | pubmed:affiliation | Department of Microbiology, University of Alabama at Birmingham 35294. | lld:pubmed |
| pubmed-article:3281909 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3281909 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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