| pubmed-article:3280481 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3280481 | lifeskim:mentions | umls-concept:C0035067 | lld:lifeskim |
| pubmed-article:3280481 | lifeskim:mentions | umls-concept:C0006938 | lld:lifeskim |
| pubmed-article:3280481 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:3280481 | lifeskim:mentions | umls-concept:C1527409 | lld:lifeskim |
| pubmed-article:3280481 | lifeskim:mentions | umls-concept:C0040395 | lld:lifeskim |
| pubmed-article:3280481 | lifeskim:mentions | umls-concept:C1516048 | lld:lifeskim |
| pubmed-article:3280481 | lifeskim:mentions | umls-concept:C0032744 | lld:lifeskim |
| pubmed-article:3280481 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:3280481 | pubmed:dateCreated | 1988-5-12 | lld:pubmed |
| pubmed-article:3280481 | pubmed:abstractText | The sequence and magnitude of acute changes in renal blood flow following administration of captopril were determined in a canine model of acute unilateral renal artery stenosis using rubidium-82 and positron emission tomography. Data were recorded in each of nine dogs under three conditions: 1) during a baseline control interval, 2) during renal artery stenosis, and 3) during stenosis with intravenous injection of captopril (1.2 mg/kg). Mean arterial blood pressure was 108 +/- 12 mm Hg at control, increased significantly to 125 +/- 13 mm Hg (p less than 0.01) during stenosis, and decreased to 98 +/- 13 mm/Hg (p less than 0.01) after captopril infusion. Mean renal blood flow was calculated using a steady state single compartment model from the images produced by positron emission tomography. The estimated flow to the affected kidney was 3.37 +/- 1.48 ml/min/g at control, 0.86 +/- 0.62 ml/min/g during stenosis (p less than 0.01), and 0.64 +/- 0.57 ml/min/g after captopril administration (p = NS compared with precaptopril value). The estimated flow to the contralateral kidney was minimally reduced from a baseline of 3.84 +/- 0.95 to 3.24 +/- 1.13 ml/min/g (p = NS) during stenosis and increased after captopril infusion (4.08 +/- 0.94 ml/min/g; p = 0.01). These data suggest that repetitive imaging with positron emission tomography can be used to delineate acute changes in renal perfusion following captopril administration. | lld:pubmed |
| pubmed-article:3280481 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3280481 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3280481 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3280481 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3280481 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3280481 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3280481 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3280481 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:3280481 | pubmed:issn | 0194-911X | lld:pubmed |
| pubmed-article:3280481 | pubmed:author | pubmed-author:TamakiNN | lld:pubmed |
| pubmed-article:3280481 | pubmed:author | pubmed-author:StraussH WHW | lld:pubmed |
| pubmed-article:3280481 | pubmed:author | pubmed-author:CorreiaJ AJA | lld:pubmed |
| pubmed-article:3280481 | pubmed:author | pubmed-author:AlpertN MNM | lld:pubmed |
| pubmed-article:3280481 | pubmed:author | pubmed-author:RabitoC ACA | lld:pubmed |
| pubmed-article:3280481 | pubmed:author | pubmed-author:Barlai-Kovach... | lld:pubmed |
| pubmed-article:3280481 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3280481 | pubmed:volume | 11 | lld:pubmed |
| pubmed-article:3280481 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3280481 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3280481 | pubmed:pagination | 217-22 | lld:pubmed |
| pubmed-article:3280481 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:3280481 | pubmed:meshHeading | pubmed-meshheading:3280481-... | lld:pubmed |
| pubmed-article:3280481 | pubmed:meshHeading | pubmed-meshheading:3280481-... | lld:pubmed |
| pubmed-article:3280481 | pubmed:meshHeading | pubmed-meshheading:3280481-... | lld:pubmed |
| pubmed-article:3280481 | pubmed:meshHeading | pubmed-meshheading:3280481-... | lld:pubmed |
| pubmed-article:3280481 | pubmed:meshHeading | pubmed-meshheading:3280481-... | lld:pubmed |
| pubmed-article:3280481 | pubmed:meshHeading | pubmed-meshheading:3280481-... | lld:pubmed |
| pubmed-article:3280481 | pubmed:meshHeading | pubmed-meshheading:3280481-... | lld:pubmed |
| pubmed-article:3280481 | pubmed:meshHeading | pubmed-meshheading:3280481-... | lld:pubmed |
| pubmed-article:3280481 | pubmed:meshHeading | pubmed-meshheading:3280481-... | lld:pubmed |
| pubmed-article:3280481 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3280481 | pubmed:articleTitle | The effect of captopril on renal blood flow in renal artery stenosis assessed by positron tomography with rubidium-82. | lld:pubmed |
| pubmed-article:3280481 | pubmed:affiliation | Department of Radiology, Massachusetts General Hospital, Boston 02114. | lld:pubmed |
| pubmed-article:3280481 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3280481 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
