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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
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|
pubmed:dateCreated |
1977-8-12
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|
pubmed:abstractText |
In eight normal weight healthy volunteers it was proved by C-peptide assay whether high concentrations of insulin in serum would suppress the secretion of insulin in an autoregulative manner. Insulin combined with glucose, therefore was given intravenously as a single bolus injection as well as an infusion over a period of two hours. Moreover it was proved whether high levels of insulin would suppress the reactivity of the B-cell to sulphonylurea administration. It was demonstrated that the secretion of the B-cell is regulated only by the concentration of the blood sugar, but not by the level of serum insulin. Likewise the stimulation of the B-cell by sulphonyl-urea administration is not suppressed by high concentrations of insulin.
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pubmed:language |
ger
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
May
|
|
pubmed:issn |
0023-2173
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
15
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|
pubmed:volume |
55
|
|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
475-9
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|
pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:327147-Blood Glucose,
pubmed-meshheading:327147-C-Peptide,
pubmed-meshheading:327147-Depression, Chemical,
pubmed-meshheading:327147-Drug Combinations,
pubmed-meshheading:327147-Glucose,
pubmed-meshheading:327147-Homeostasis,
pubmed-meshheading:327147-Humans,
pubmed-meshheading:327147-Insulin,
pubmed-meshheading:327147-Islets of Langerhans,
pubmed-meshheading:327147-Sulfonylurea Compounds
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|
pubmed:year |
1977
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|
pubmed:articleTitle |
[Studies on the question of a possible autoregulation of insulin secretion (author's transl)].
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pubmed:publicationType |
Journal Article,
English Abstract
|
