Linked Life Data

3266382

Source:http://linkedlifedata.com/resource/pubmed/id/3266382

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-5-2
pubmed:abstractText
In the previous report we found that IL-1-like activity in horny tissue extracts from patients with psoriasis vulgaris and related sterile pustular dermatoses was remarkably low as compared to that in orthokeratotic horny tissue extracts prepared from non-inflammatory skin. In this report we studied the inhibitory activity of lesional horny tissue extracts from three psoriatics on recombinant IL-1-induced thymocyte proliferation in order to search for a possible coexistence of substances which may inhibit thymocyte proliferation. However, we failed to demonstrate any remarkable IL-1 inhibitory activity in each fraction after gel filtration high-performance liquid chromatography of the psoriatic scale extracts or in that of extracts from the plantar callus. We conclude that IL-1 stores are decreased in the pathologic horny layers of psoriatic lesions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0040-8727
pubmed:author
pubmed:issnType
Print
pubmed:volume
156
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
149-56
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Absence of IL-1 inhibitor in psoriatic scale extracts.
pubmed:affiliation
Department of Dermatology, Tohoku University School of Medicine, Sendai, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't