Linked Life Data

3265669

Source:http://linkedlifedata.com/resource/pubmed/id/3265669

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1989-3-30
pubmed:abstractText
The authors examined the binding nature of mibolerone in cytosols of hypertrophic prostates from 15 patients to androgen receptor using Dextran-charcoal assay, analyzed it by the method of Scatchard, and compared it with that of R1881. The addition of triamcinolone acetonide into the incubation medium induced specific single binding of mibolerone to androgen receptor with high affinity as well as R1881. The receptor contents obtained with mibolerone were higher than those of R1881, and both of them correlated well. The dissociation constants of both ligands showed good correlation and no significant differences. Mibolerone seems to be as suitable a ligand as R1881 for measuring the androgen receptor.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0029-0661
pubmed:author
pubmed:issnType
Print
pubmed:day
20
pubmed:volume
64
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
655-65
pubmed:dateRevised
2011-7-27
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
[Comparison of the binding nature of mibolerone to androgen receptor of human prostate with that of R1881].
pubmed:affiliation
2nd Department of Surgery, School of Medicine, University of Tokushima, Japan.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro, English Abstract