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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1989-2-16
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pubmed:abstractText |
Interleukin-2 receptor (IL-2R) is expressed on activated lymphocyte after stimulation with antigen or interleukin-2 (IL-2), meanwhile soluble form of the receptor is released. Using enzyme-linked immunosorbent assay, serum IL-2R levels were determined in 34 healthy controls, 61 patients with systemic lupus erythematosus (SLE) and 32 patients with rheumatoid arthritis (RA), yielding mean +/- SD values of 355 +/- 89, 807 +/- 453 and 567 +/- 210 U/ml respectively. In both SLE and RA patients, the active disease group had more markedly elevated serum IL-2R levels compared with those of the inactive group. In patients with SLE, elevated serum IL-2R is associated with lymphopenia, renal disorders, decreased C3 level and increased anti-DNA, thus make it a good parameter to monitor disease activity in SLE.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0253-2662
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
16-22
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3264781-Adolescent,
pubmed-meshheading:3264781-Adult,
pubmed-meshheading:3264781-Arthritis, Rheumatoid,
pubmed-meshheading:3264781-Female,
pubmed-meshheading:3264781-Humans,
pubmed-meshheading:3264781-Lupus Erythematosus, Systemic,
pubmed-meshheading:3264781-Male,
pubmed-meshheading:3264781-Middle Aged,
pubmed-meshheading:3264781-Receptors, Interleukin-2
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pubmed:year |
1988
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pubmed:articleTitle |
Serum interleukin-2 receptor in systemic lupus erythematosus and rheumatoid arthritis.
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pubmed:affiliation |
Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, ROC.
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pubmed:publicationType |
Journal Article
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