Linked Life Data

3261398

Source:http://linkedlifedata.com/resource/pubmed/id/3261398

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-9-21
pubmed:abstractText
Extensive diagnostic measures are necessary to clarify the indication for surgery in patients suffering from epilepsy that is refractory to treatment. Within the overall framework of neuropsychological diagnosis we conducted the Wada test, injecting 200 mg (or 3 mg/kg body weight) of sodium amytal on different days, in each case into the left or right internal carotid artery. This results in a 3-5 minute anaesthesia of the relevant hemisphere. By means of a neuropsychological short test it is possible to determine the performance of the non-blocked hemisphere. The extent of the blocking is also determined by simultaneous i.v. injection of HM-PAO (hexamethyl propylene amine oxime) labelled with 99m Tc, the uptake of which by various cerebral regions is visualised via SPECT. The Wada test supplies information on the lateralisation of cognitive functions (speech, memory etc.) whereas the SPECT examination enables additional determinations not only of processes that must be characterised as diaschisis, but also on the extent of blocking of a hemisphere. The results supply clues to expected postoperative cognitive deficits and thus enable a differentiated assessment of the indication for surgery. This is discussed on the basis of two clinical cases.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0028-3819
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
96-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
[Preoperative diagnosis: the Wada test with SPECT control for localizing brain function in therapy-refractory epilepsy].
pubmed:affiliation
Abteilung für Klinische Neurophysiologie, Neurochirurgischen Universitätsklinik Bonn.
pubmed:publicationType
Journal Article, English Abstract, Case Reports