Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6 Suppl
pubmed:dateCreated
1988-9-8
pubmed:abstractText
The combination of ticarcillin disodium/clavulanate potassium is a potent, irreversible inhibitor of beta-lactamase that is active against a broad spectrum of gram-positive and -negative bacteria, which often are found in the polymicrobial infection of postcesarean endomyometritis. Eighty-four randomly chosen women with postcesarean endomyometritis received 3 g ticarcillin disodium plus 100 mg clavulanate potassium intravenously every six hours. The drug was discontinued after patients were afebrile and asymptomatic for 72 hours. The mean duration of therapy was 4.7 days. A clinical cure was achieved in 56 of the 70 evaluable patients (80%); 14 were clinical failures. Six of the 70 patients (9%) were bacteremic. One hundred eighty-five aerobic bacteria and 109 anaerobic bacteria were isolated. Of the 96 aerobic isolates tested, 75 (78%) were beta-lactamase positive, as were 68 of the 78 anaerobic isolates (87%).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0024-7758
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
584-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Ticarcillin disodium and clavulanate potassium in the treatment of post-cesarean-section endomyometritis.
pubmed:affiliation
Department of Internal Medicine, Louisiana State University School of Medicine, New Orleans 70112.
pubmed:publicationType
Journal Article