Linked Life Data

3260018

Source:http://linkedlifedata.com/resource/pubmed/id/3260018

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-7-22
pubmed:abstractText
Specific, saturable and reversible binding of [3H]inositol 1,4,5-triphosphate (IP3) was demonstrated to membranes prepared from autopsied cerebral cortices from 6 subjects who were free from psychiatric or neurological disease. The binding has an affinity of 27 +/- 8 nM (mean +/- S.E.M.); capacity (Bmax) of 1.09 +/- 0.18 pmol/mg protein and is reversible in the presence of an excess of unlabelled IP3. These [3H]IP3 binding sites are likely to be physiologically significant receptors which merit further characterization in the normal and diseased human brain.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
3
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
283-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
[3H]inositol 1,4,5-triphosphate binding in human cerebral cortex.
pubmed:affiliation
Department of Psychiatry, University of Toronto, Ont., Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't