Linked Life Data

3259554

Source:http://linkedlifedata.com/resource/pubmed/id/3259554

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1988-7-14
pubmed:abstractText
The effects of T-2 toxin on the antibody producing ability of CD-1 mice after dietary exposure to 0, 2.5, 5 and 15 ppm of T-2 toxin for 29 days was studied. The antibody response against sheep red blood cells, a T-lymphocyte and macrophage-dependent response was suppressed at 2.5, 5 and 15 ppm of T-2 toxin exposure. In contrast, the antibody responses against dinitrophenyl-aminoethylcarbamylmethyl - Ficoll (DNP - Ficoll), a T-lymphocyte independent macrophage-dependent response, and Escherichia coli 0127 (LPS), a T-lymphocyte and macrophage-independent response, were not affected. These results suggest that the inhibitory effects of T-2 toxin on antibody-producing ability after subacute dietary exposure appear to be a direct affect on T-lymphocyte function, possibly involving the T-helper lymphocytes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0192-0561
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
145-51
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Antibody producing ability of mouse spleen cells after subacute dietary exposure to T-2 toxin.
pubmed:affiliation
Department of Veterinary Physiological Sciences, University of Saskatchewan, Saskatoon, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't