Linked Life Data

3251583

Source:http://linkedlifedata.com/resource/pubmed/id/3251583

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1989-7-31
pubmed:abstractText
The laminar distribution of gamma-aminobutyric acid (GABA) was studied in certain structures of the visual system of the adult cat. A microassay method to measure GABA (10(-12) mol) was established using enzymatic cycling of NADP-NADPH. In the dorsal lateral geniculate nucleus, GABA concentration was highest in lamina A (average concentration 23 mmol/kg dry weight) and lowest in lamina C. In the visual cortex (Areas 17 and 18), the concentration of GABA was 10-12 mmol/kg dry weight in layers I-IV and 5-8 mmol/kg dry weight in layers V and VI. No significant difference was found in the GABA distribution in Areas 17 and 18. In the superior colliculus, the highest level of GABA was found in the upper part of the superficial gray layer (40 mmol/kg dry weight), whereas the deep layers contained GABA at a concentration of 23-28 mmol/kg dry weight. The results of the GABA distribution measurements revealed an orderly, layer-specific disposition of the neurotransmitter in the cat visual system. GABA may play an important role in the function of the visual system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
451
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
172-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Laminar distribution of GABA (gamma-aminobutyric acid) in the dorsal lateral geniculate nucleus, Area 17 and Area 18 of the visual cortex, and the superior colliculus of the cat.
pubmed:affiliation
Department of Physiology, School of Medicine, Kobe University, Japan.
pubmed:publicationType
Journal Article